Diamond Retinal 5

Formulated with 0.05% pure Retinal to improve skin texture and uneven skin tone. Helps to minimize the appearance of fine lines and wrinkles. All skin types

Specially formulated with advanced liposomal delivery system to ensure stability and provide slow release of high-potency retinaldehyde to mazimize anti aging benefits and minimize irritation. 
Boosts collagen production to help diminish fine lines and wrinkles as tighten and firm the skin.
Reduces brown spots and brightens skin. Provides a more even skin tone. 
Softens and smooths rough skin texture.
Contains multiple antioxidants to neutralize free radicals and prevent future damage.
Helps to calm and soothe inflamed and irritated skin. 

Size 30 ml / 0.1 fl.oz.
pH :5.0-5.5

Aqua, Caprylic/Capric Triglyceride, Dipropylheptyl Carbonate, Glycerin, Glyceryl Stearate, Cetyl Stearyl Alcohol, Phospholipids, Niacinamide, 3-O-Ethyl Ascorbic Acid, Ascorbic Acid, Sodium Polyacrylate, Squalane, Phenoxyethanol, Retinal, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Butylene Glycol, Carbomer, Polysorbate 20, Xanthan Gum, Ethylhexylglycerin, Tocopherol

Aqua, Caprylic/Capric Triglyceride, Dipropylheptyl Carbonate, Glycerin, Glyceryl Stearate, Cetyl Stearyl Alcohol, Phospholipids, Niacinamide, 3-O-Ethyl Ascorbic Acid, Ascorbic Acid, Sodium Polyacrylate, Squalane, Phenoxyethanol, Retinal, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Butylene Glycol, Carbomer, Polysorbate 20, Xanthan Gum, Ethylhexylglycerin, Tocopherol

When to Use: PM only. Retinal is photolabile — retinoic acid-driven cell renewal is an overnight process. Always apply SPF the following morning.

Application Steps:

Cleanse and pat skin completely dry
Apply Cyrène Hyaluronic Acid Intensifier first if using — allow to absorb
Dispense 1 pump onto fingertips
Press gently across the face and neck; avoid the immediate eye orbit and lip margin
Allow 60 seconds to absorb fully
Seal with Cyrène CeraPep Barrier Support Moisturiser

Re-introduction Frequency — Even For Established Retinoid Users:

Weeks 1–2: Two to three applications per week
Weeks 3–4: Four to five applications per week
Week 5 onwards: Nightly, as tolerated

Pro Clinic Tip: At 0.05% retinal, the retinoic acid conversion rate at the skin surface is measurably higher — meaning results accumulate faster, but so does the cost of inconsistency. A stable, uninterrupted nightly protocol produces exponentially better outcomes than intermittent high-frequency use. Prioritise consistency over intensity.

Next Step In The Series: For those requiring the highest available non-prescription retinal concentration, Diamond Retinal 10 delivers the next threshold in the series.

Pairs Best With

Cyrène CeraPep Barrier Support Moisturiser — Essential at this retinal strength. Apply as the final PM step to reinforce the stratum corneum and sustain skin integrity through accelerated retinoic acid-driven turnover.
Cyrène Hyaluronic Acid Intensifier — Apply first on slightly damp skin. Provides a hydration base that supports comfort and barrier resilience throughout the renewal process.
Cyrène Buffet Multi Peptide Complex Serum — For an amplified collagen protocol, layer before Diamond Retinal 5. The combined peptide activity of Matrixyl 3000 within both formulas compounds retinoic acid-mediated fibroblast stimulation.
Cyrène Invisible Physical Sunscreen SPF50 — Non-negotiable the following morning. At 0.05% retinal, photosensitivity is significantly elevated; broad-spectrum mineral SPF is not optional.

Do Not Combine In The Same Routine

AHAs & BHAs (Glycolic, Lactic, Salicylic Acid) — At this retinal concentration, combining chemical exfoliants in the same routine risks serious barrier compromise. Strictly alternate on different evenings.
L-Ascorbic Acid Vitamin C — Reserve for the AM routine. The formula's dual Vitamin C system is sufficient; additional L-Ascorbic Acid at night is unnecessary.
Benzoyl Peroxide — Oxidises and degrades retinal on contact. Do not combine.
Other Retinoid Products — Do not layer additional retinol or retinal formulations in the same PM routine.

What does retinal actually do to the skin?
Retinal (retinaldehyde) is converted by the skin into retinoic acid — the biologically active form that directly binds to nuclear receptors within skin cells. This binding triggers a regulated programme of gene expression: collagen synthesis accelerates, cellular turnover increases, melanin production is suppressed, and keratinocyte differentiation normalises. The result, over consistent use, is visibly smoother texture, reduced fine lines, more even skin tone, and improved skin density. Retinal achieves this one step faster than retinol because it requires only one enzymatic conversion to become retinoic acid, compared to two for retinol.

How is Diamond Retinal 5 different from the other products in the Diamond Retinal series?
Diamond Retinal 5 contains 0.05% retinaldehyde — five times the concentration of Diamond Retinal 1 (0.01%) and approximately 1.7 times that of Diamond Retinal 3 (0.03%). The formula is also more streamlined: at this retinal level, the architecture focuses on amplified phospholipid liposomal delivery, peptide-driven collagen stimulation via Matrixyl 3000, and dual Vitamin C protection. It is designed for skin that has established full retinoid tolerance through the earlier steps of the series and is ready for intensive, sustained retinoic acid-level skin renewal.

How long does it take to see results from a retinal serum?
Initial improvements in skin luminosity and texture are typically visible within four to six weeks of consistent use — one full skin cell turnover cycle. Clinically significant reductions in fine lines, pigmentation, and skin laxity generally require eight to sixteen weeks of regular application. Retinoic acid-mediated collagen remodelling is a sustained biological process; the most meaningful results accumulate over three to six months of consistent nightly use. Starting at two to three applications per week and building to nightly use over four weeks produces the best long-term outcomes with the lowest risk of adjustment-period sensitivity.

Can Diamond Retinal 5 replace my prescription retinoid?
Diamond Retinal 5 is not a prescription product and makes no therapeutic claims. However, retinaldehyde has been independently studied as the non-prescription retinoid with the closest efficacy profile to prescription-grade tretinoin, achieved at lower concentrations and with a significantly improved tolerability profile. For those taking breaks from or stepping down from prescription retinoids, Diamond Retinal 5 provides meaningful retinoic acid-adjacent activity that sustains skin renewal momentum without requiring a prescription. Any decision to modify or discontinue a prescribed treatment should involve a dermatologist or prescribing clinician.

Is retinal suitable for darker skin tones?
Yes — and retinal is particularly relevant for darker skin tones because its conversion to retinoic acid directly suppresses tyrosinase activity, the enzyme responsible for melanin overproduction. This makes it clinically effective for post-inflammatory hyperpigmentation, melasma, and uneven tone — concerns that disproportionately affect deeper skin tones. The liposomal delivery system in Diamond Retinal 5 reduces the risk of retinoid-induced irritation, which in darker skin can itself trigger post-inflammatory pigmentation. Introduce gradually and pair consistently with a high-SPF mineral sunscreen.